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Plasma Cell Tumor Removed Without Clear Margins From a Paw

Reader Question
My 10 1/2 yr old Cocker Spaniel just had a plasma cell tumor removed from in between the pads of his front left foot. It grew quite rapidly and looked like a cherry tomato. I was told by the vet that it was cancerous. What are my treatment options? Is there anything I can do to reduce the chance of it returning? Are there other options besides waiting to see if it returns? My vet made it clear that he couldn't get a "clear margin" during the removal due to the location of the tumor. I'm really concerned for the well-being of my dog. He has already had both eyes removed and I'm now concerned about having him loose his paw.

He has begun to get numerous wart-like growths all over his body but those seem to be benign. I had 3 of those removed and tested and they were benign. The growth in his foot was distinctly different. My dog has otherwise been quite healthy.


Answer from Our Team

Skin plasma cell tumors (plasmacytomas) are technically a cancer of plasma cells, but most skin plasmacytomas behave in a low-grade, benign way, and surgery cures most of them. Even when margins aren't completely clear, many don't come back, which is why watchful waiting is a common approach.

Ask your vet to go over the pathology report with you, including the margins, check nearby lymph nodes, and recheck the site every few weeks. If it regrows, options include a second surgery or radiation therapy, which these tumors usually respond to well and can avoid amputation. A veterinary oncologist can go over options. Keep a photo log of the new wart-like growths too.

See lumps and bumps on dogs.

This is general information, not a diagnosis. Please follow your own vet's advice.

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