Skin and soft-tissue tumors are the most common tumors in dogs, and most are benign.1,2 But somewhere between about 1 in 5 and 2 in 5 skin tumors that reach a lab turn out to be cancer.2,3,4 The most common skin cancer in dogs is the mast cell tumor. Others include soft tissue sarcomas, squamous cell carcinoma and melanoma.2,5,6 You can't tell a cancer from a harmless lump by looking at it or feeling it, so the safest habit is simple: have any lump the size of a pea that has been there for a month checked by your vet.7,6
See your vet promptly if you notice:
- A lump about the size of a pea (1 cm) or larger that has been there for a month, or any lump that is growing7
- A sore that won't heal, or red, crusty, thickened skin on pale, thin-haired areas such as the belly or nose8,6
- A swollen toe, especially with a lost or broken nail, in an older dog6,9
- A dark or pigmented growth on the lips, in the mouth or at a nail bed10,11
- A lump that changes size from day to day, or becomes red, swollen or ulcerated5
What the Research Says
- Most skin tumors are benign. In a Danish cancer registry of 765 skin tumors, 66% were benign and 21% malignant. A Portuguese lab series found 37% malignant.2,3
- Mast cell tumors lead the list, making up roughly 1 in 5 to 1 in 6 canine skin tumors.5,12,3
- Needle samples help. A fine-needle aspirate matched the lab biopsy result in about 9 in 10 skin lumps in one study.13
- Type and grade matter more than anything. For mast cell tumors, low-grade tumors are often cured by surgery, while high-grade tumors carry a much shorter outlook.14,12
Common Types of Skin Cancer in Dogs
Mast cell tumors
The most common skin cancer in dogs, usually in dogs around 8 to 10 years old. They can look like almost anything, including a soft lump that feels like a fatty lipoma, and they can swell and shrink from day to day.6,5,14 Boxers, Boston Terriers, Staffordshire Bull Terriers and Labradors are among the breeds at higher risk.5,14 See mast cell tumors in dogs.
Show photo: mast cell tumors on a dog's legs
Soft tissue sarcomas
Tumors of the connective tissue under the skin. They may feel soft or firm and can be mistaken for fatty lumps. They make up about 15% of skin and under-skin tumors.15,16 They tend to grow back if not removed completely, so the first surgery is the best chance of a cure. Most low-grade sarcomas don't spread, but high-grade ones can.17,16,15
Squamous cell carcinoma (SCC)
About 5% of canine skin tumors. Many are linked to sun exposure on pale, thinly haired skin, especially the belly and groin of white, short-coated breeds such as Dalmatians, Bull Terriers, pit bull types, Beagles and Whippets.18,6,8 Sun damage often starts as red, crusty, thickened skin.8,6 SCC can also grow under a toenail, mainly in older, large, dark-coated dogs such as Giant and Standard Schnauzers, Standard Poodles and Gordon Setters.19,9 SCC is locally invasive but less likely to spread than many cancers.18
Melanoma
Pigmented growths on haired skin are usually benign (melanocytomas).10,20 Melanomas in the mouth, on the lips or in a nail bed are much more likely to be malignant and to spread.10,11,9 Breed matters too: most skin melanomas are benign in Dobermans and Miniature Schnauzers, while most are malignant in Miniature Poodles.20
Other skin tumors
Basal cell tumors (many now called trichoblastomas) are common, usually benign, and often cured by surgery.6,19 Skin lymphoma and other rarer cancers also occur, and a biopsy is needed to tell them apart.12,1
Show photo: a skin tumor on a dog's head
How Vets Diagnose Skin Cancer
- Fine-needle aspirate: a quick needle sample, often done in the exam room without sedation. It identifies many tumors, including most mast cell tumors.1,5,13
- Biopsy: a small piece of tissue, or the whole lump, sent to a pathologist. It's needed for a definite diagnosis and to grade the tumor.1,5
- Staging: for cancers that may spread, your vet may check the nearby lymph nodes and do chest X-rays or an abdominal ultrasound.5
Knowing the type before surgery helps your vet plan how much tissue to remove. Sarcomas in particular shouldn't be "shelled out," because cells left behind make them grow back.17
Treatment
- Surgery is the main treatment for most skin cancers. Malignant tumors are removed with a margin of normal tissue around them, often 2 to 3 cm.1,6,5
- Radiation therapy is often used when a tumor can't be fully removed.5,17
- Chemotherapy and targeted drugs are used for cancers that have spread or are high grade.5,12
- Other options for some tumors include electrochemotherapy (a chemotherapy drug combined with electric pulses) and, for oral melanoma, immunotherapy.12,21,11
A veterinary oncologist can explain which options fit your dog's tumor type, grade and overall health.
Outlook
The outlook depends on the type, grade and stage of the cancer and whether it can be fully removed. Many low-grade mast cell tumors, low-grade sarcomas and sun-related SCCs caught early are cured with surgery.14,16,18 Melanomas of the mouth and nail bed and high-grade tumors are more serious.11,9,14 Finding lumps early, while they're small, gives the best chance of complete removal.7
Prevention and Early Detection
- Check your dog monthly. Run your hands over the whole body, including between the toes and inside the lips, and note any lumps.22
- Follow the pea-and-a-month rule: have any lump 1 cm or larger that has been there for a month sampled, and don't let a lump grow past that size without having it checked.7
- Limit sun for pale, thin-coated dogs. Keep them indoors in the middle of the day on sunny days, use shade, and ask your vet about a dog-safe sunscreen or protective shirt. Don't use human sunscreen without checking first.8,19
See also lumps and bumps on dogs, signs of cancer in dogs and cancer in dogs.
Frequently Asked Questions
What does skin cancer look like on a dog?
It can look like almost anything: a lump under the skin, a red or raw bump, a sore that won't heal, or a dark growth. That's why lumps need a needle sample.
What is the most common skin cancer in dogs?
Mast cell tumors.
Can dogs get skin cancer from the sun?
Yes. Squamous cell carcinoma is linked to sun exposure on pale, thinly haired skin.
How long can a dog live with skin cancer?
It varies widely by type and grade. Many dogs are cured by surgery, while aggressive types have a shorter outlook. Your vet can give a more specific answer after a biopsy.
Are cancerous lumps on dogs hard or soft?
Either. Some cancers feel soft and movable, like a fatty lump.
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Sources and further reading
This article was rewritten and fact-checked on October 20, 2026 against current veterinary references and specialist guidelines:
- Villalobos AE. Overview of Tumors of the Skin and Soft Tissues in Animals. Merck Veterinary Manual, Professional Version, reviewed August 2021, updated September 2024.
- Brønden LB, Eriksen T, Kristensen AT. Mast cell tumours and other skin neoplasia in Danish dogs - data from the Danish Veterinary Cancer Registry. Acta Veterinaria Scandinavica 52:6, January 22, 2010.
- Martins AL, Canadas-Sousa A, Mesquita JR, Dias-Pereira P, Amorim I, Gärtner F, et al. Retrospective study of canine cutaneous tumors submitted to a diagnostic pathology laboratory in Northern Portugal (2014-2020). Canine Medicine and Genetics 9:2, February 25, 2022.
- Bacon N. Practical Review of Common Skin and Subcutaneous Tumours: Dogs and Cats. EVC Voorjaarsdagen Amsterdam proceedings (IVIS), 2013.
- American College of Veterinary Surgeons. Mast Cell Tumors. ACVS, last modified November 14, 2024.
- Villalobos AE. Tumors of the Skin in Dogs. Merck Veterinary Manual, Pet Owner Version, reviewed June 2018, updated April 2026.
- Ettinger SN. Tumor Detection in Dogs and Cats: See Something, Do Something. Today's Veterinary Practice, July/August 2017.
- Weir M. Solar Dermatitis in Dogs. VCA Animal Hospitals, updated September 11, 2026.
- Veterinary Society of Surgical Oncology. Digit Tumors. VSSO, 2019.
- Villalobos AE. Tumors of Melanocytic Origin in Animals. Merck Veterinary Manual, Professional Version, updated November 2024.
- Veterinary Society of Surgical Oncology. Oral Melanoma. VSSO, 2019.
- Villalobos AE. Lymphocytic, Histiocytic, and Related Cutaneous Tumors in Animals. Merck Veterinary Manual, Professional Version, reviewed August 2021, updated June 2026.
- Ghisleni G, Roccabianca P, Ceruti R, Stefanello D, Bertazzolo W, Bonfanti U, Caniatti M. Correlation between fine needle aspiration cytology and histopathology in the evaluation of cutaneous and subcutaneous masses from dogs and cats. Veterinary Clinical Pathology 35(1):24-30, 2006.
- Veterinary Society of Surgical Oncology. Skin MCT - Canine. VSSO, 2019.
- Veterinary Society of Surgical Oncology. Skin Soft Tissue Sarcoma. VSSO, 2019.
- Cornell Richard P. Riney Canine Health Center. Soft Tissue Sarcomas in Dogs. Cornell University College of Veterinary Medicine, updated May 2025.
- Villalobos AE. Connective Tissue Tumors in Animals. Merck Veterinary Manual, Professional Version, reviewed August 2021, updated June 2026.
- Veterinary Society of Surgical Oncology. Skin SCC - Canine. VSSO, 2019.
- Villalobos AE. Epidermal and Hair Follicle Tumors in Animals. Merck Veterinary Manual, Professional Version, reviewed August 2021, updated June 2026.
- Veterinary Society of Surgical Oncology. Skin Melanoma - Canine. VSSO, 2019.
- Spugnini EP, Baldi F, Mellone P, Feroce F, D'Avino A, Bonetto F, Vincenzi B, Citro G, Baldi A. Patterns of tumor response in canine and feline cancer patients treated with electrochemotherapy: preclinical data for the standardization of this treatment in pets and humans. Journal of Translational Medicine 5:48, October 2, 2007.
- Berman-Thacker E. Skin Tags on Dogs. PetMD, May 9, 2023.
About this article
Last updated : fully rewritten using cancer registry and laboratory studies, the Merck Veterinary Manual, the American College of Veterinary Surgeons, the Veterinary Society of Surgical Oncology, Cornell and VCA.
This page is for general information and is not a substitute for an exam by your veterinarian.