Tick-Borne Diseases in Dogs

Key takeaways

  • The main tick diseases in US dogs are Lyme disease, anaplasmosis, ehrlichiosis, Rocky Mountain spotted fever, babesiosis and hepatozoonosis.
  • Signs usually appear 1 to 3 weeks or more after a bite, and many infected dogs never get sick.
  • A positive screening test means exposure, not illness, so your vet decides whether to treat.
  • Most dogs recover with a few weeks of antibiotics when treated early.
  • Year-round tick prevention is recommended, because some germs pass from a tick within hours.

The main tick-borne diseases in US dogs are Lyme disease, anaplasmosis, ehrlichiosis, Rocky Mountain spotted fever, babesiosis and hepatozoonosis.1,2,3,4 Common signs are fever, tiredness, poor appetite, lameness or swollen joints, and with some diseases bruising, bleeding or pale gums, usually appearing 1 to 3 weeks or more after a bite.5,2,6,7 Most of these infections respond well to a few weeks of antibiotics when treated early, although babesiosis and hepatozoonosis need antiprotozoal medicines and can be harder to clear.8,9,3,4 Many infected dogs never get sick, so your vet should confirm the diagnosis rather than relying on a positive screening test alone.8,6

See a vet urgently if your dog has:

  • A high fever, especially with swelling or pain10
  • Nosebleeds, unusual bruising or tiny red spots on the gums or skin2,10,6
  • Pale or yellow gums, or dark red-brown urine11,3
  • Sudden lameness with fever, or wobbliness, weakness or seizures8,10,2

Rocky Mountain spotted fever can be dangerous when treatment is delayed, so vets often start treatment before test results come back.10

What the Research Says

  • Exposure is common in some regions. In more than 144 million US dog test results from 2013 to 2019, 12.1% of dogs in the Northeast had Lyme antibodies and 7.3% had Anaplasma antibodies; in the Southeast, 5.2% had Ehrlichia antibodies.12
  • Ehrlichia positivity is rising. It rose in every US region and fourfold in the Southeast, partly because newer tests detect more species.12
  • Most Lyme-positive dogs stay healthy. A US specialist panel says most dogs with Lyme antibodies show no signs, and protein in the urine (a sign of kidney involvement) appears in under 2% of them.8
  • Treated dogs improve quickly. Dogs with acute ehrlichiosis usually improve dramatically within 24 to 48 hours of starting antibiotics, and Lyme arthritis responds within 1 to 3 days.9,8
  • Prompt RMSF treatment saves lives. Fewer than 5% of affected dogs die, according to a 2022 specialist review, and delays raise the risk.13,10

Tick-Borne Diseases at a Glance

DiseaseMain US tickWhere most commonTypical signs
Lyme diseaseBlack-legged (deer) tick1,14Northeast, Upper Midwest12Shifting lameness, swollen joints, fever; rare kidney form8,14
AnaplasmosisBlack-legged ticks; brown dog tick for one species6Northeast, northern Midwest6,12Fever, lethargy, lameness, bruising6,15
EhrlichiosisBrown dog tick; lone star tick2Southeast, Southwest, south-central2,12Fever, bleeding, swollen lymph nodes, weight loss2,16
Rocky Mountain spotted feverAmerican dog tick, Rocky Mountain wood tick10Southeast, south-central10High fever, pinpoint bleeding, swelling, joint and nerve signs10
BabesiosisTicks; also dog bites and transfusions11Southern US11Anemia, pale gums, dark urine, jaundice, fever11,3
HepatozoonosisGulf Coast tick, swallowed rather than biting4Gulf Coast states, spreading4Fever, severe muscle pain, stiffness, eye discharge4

Dogs can carry more than one infection at once, which can make signs more severe.8,6 Parasite experts publish county-level maps of positive tests across the US; a low-risk area is not a no-risk area.17

Lyme Disease

Lyme disease is caused by bacteria carried only by Ixodes ticks, the black-legged or deer tick.1 Up to half of ticks are infected in some areas.7 Most exposed dogs never get sick.8,18 Dogs that do usually develop:

  • Lameness that may shift from leg to leg, with swollen, painful joints7,14
  • Fever, low energy, poor appetite and swollen lymph nodes8,7

Lyme arthritis is most common in young, often large, outdoor dogs.8 Read more on our pages about canine Lyme disease symptoms, Lyme disease signs in dogs and Lyme disease in dogs.

Lyme kidney disease (Lyme nephritis)

Lyme kidney disease is rare, but it is serious and can be fatal.18,7,19 Retriever breeds seem to be over-represented.8 That's why vets check the urine for protein in dogs that test positive.8 See kidney disease in dogs.

Are there stages of Lyme disease in dogs?

Dogs don't follow the staged pattern described in people. Most infected dogs have no signs, a smaller group get arthritis, and a rare few develop kidney disease.8,18

Anaplasmosis

One form of anaplasmosis infects white blood cells and is spread by black-legged ticks, the same ticks that carry Lyme. Another form infects platelets and is spread by the brown dog tick.6 Most infections cause no signs.6 When dogs do get sick, about 1 to 2 weeks after a bite, they may have fever, poor appetite, lethargy, lameness, swollen lymph nodes, and bruising or pinpoint bleeding from low platelets.6,15 Signs usually clear within about a week of starting antibiotics.6

Ehrlichiosis

Ehrlichiosis is spread by tick bites, mainly the brown dog tick and the lone star tick.16,2 The acute stage starts 1 to 3 weeks after infection, with fever, bleeding tendencies, an enlarged spleen and swollen lymph nodes, and sometimes nerve signs.2 Most dogs clear the infection within 2 to 4 weeks.2 A rare chronic form can damage the bone marrow, eyes, joints and kidneys, and it's more common in German Shepherd Dogs.2 Recovery doesn't give lasting immunity, so dogs can be reinfected.9

Rocky Mountain Spotted Fever

Rocky Mountain spotted fever (RMSF) is spread by the American dog tick and the Rocky Mountain wood tick, and by the brown dog tick in parts of Arizona and Mexico. Most US cases are in the southeastern and south-central states.10 Signs include fever up to 105°F, pinpoint bleeding, swollen lymph nodes, joint pain, swelling, and breathing, eye or nerve signs. Severe cases can lead to tissue death (gangrene) in the extremities and a body-wide clotting disorder.10 Response to treatment is usually dramatic, but dogs with nerve damage may keep some deficits.10

Babesiosis

Babesiosis is caused by parasites that destroy red blood cells. It spreads through tick bites, and also through dog fights and bites, blood transfusions and from mother to puppies.11 In North America most cases are in the southern US. One species is most common in Pit Bull-type dogs, and Greyhounds are also at higher risk.11 Signs include lethargy, pale gums, fever, dark urine, jaundice and weight loss, ranging from mild to rapidly fatal.11,3 Treatment uses antiprotozoal drugs plus supportive care such as transfusions. Survivors may stay infected and relapse, and they should never be blood donors.11 One species is not readily cleared by standard medicines.3

Hepatozoonosis

American canine hepatozoonosis is unusual: dogs catch it by swallowing an infected Gulf Coast tick, or by eating infected rodents or rabbits, not from a bite. It was first found on the Texas Gulf Coast and has spread north and east with the tick.4 Signs include a high fever that doesn't respond to antibiotics, severe muscle pain, stiffness, weakness, eye discharge and weight loss.4 Treatment is a short course of combined medicines followed by long-term antiprotozoal medicine for at least 2 years. It isn't curative, and many dogs relapse, but quality of life can be good with care.4

How Soon After a Tick Bite Do Dogs Get Sick?

Signs of tick-borne disease may not appear for 7 to 21 days or longer after a bite.5 Ehrlichiosis usually shows up in 1 to 3 weeks and anaplasmosis in 1 to 2 weeks.2,15 Lyme signs, if any, appear weeks to a few months after the bite.18,19

How fast ticks pass on infection

Lyme bacteria usually need a tick attached for a day or two, so quick removal helps.1,8,7 Anaplasma also needs about 24 to 48 hours.15,13 Some other tick germs, such as Ehrlichia and the RMSF bacterium, can pass in just a few hours, which is why prevention products matter more than tick checks alone.1,10 Learn how to safely do tick removal from dogs, and see tick bite pictures. Some infections can enter through broken skin, so take care when handling ticks.20

Testing for Tick-Borne Diseases

Many vets use an in-clinic screening blood test for tick diseases and heartworm.8,2

  • A positive screening test means exposure, not illness. It doesn't prove a tick disease is causing your dog's signs or predict that your dog will get sick.8
  • Early tests can be negative. Lyme antibodies take about 4 to 6 weeks to appear, and anaplasmosis tests can be negative in the first week.14,7,6 Vets shouldn't stop treating ehrlichiosis just because an early test is negative.2
  • Follow-up tests include a blood count (low platelets are common), repeat antibody tests a few weeks apart, PCR tests that detect the germ itself, and a urine protein check for Lyme-positive dogs.2,10,3,8

Does a healthy dog that tests positive need treatment?

Not always. A positive screening test means exposure. Many healthy positive dogs are monitored, with a urine protein check for Lyme, rather than treated, and your vet will decide.8,9

Treatment and Recovery

  • Lyme disease: a tetracycline-class antibiotic for about 4 weeks. Dogs with Lyme arthritis should improve within 1 to 3 days. Some keep long-term joint pain, and infection can persist.8,7
  • Ehrlichiosis: a tetracycline-class antibiotic for about 4 weeks. Most dogs improve within 24 to 48 hours, and platelets usually return to normal within 2 weeks. Chronic cases recover more slowly.9,2
  • Anaplasmosis: a tetracycline-class antibiotic, often for at least 10 days; signs usually resolve within a week.13,6
  • RMSF: a tetracycline-class antibiotic, usually for about a week, longer if other infections are suspected, started before test results are back.10
  • Babesiosis and hepatozoonosis: antiprotozoal medicines plus supportive care; outlook is more guarded.11,4

Your vet will choose the medicine and amount for your dog.

Can a dog recover from a tick-borne disease?

Usually, yes, when treated early. Most dogs with Lyme arthritis, anaplasmosis or acute ehrlichiosis recover fully.8,6,9 The outlook is worse for Lyme kidney disease, chronic ehrlichiosis, RMSF when treatment is delayed, hepatozoonosis and some forms of babesiosis.7,2,10,4,3 Your vet can estimate your dog's outlook.

What if months have passed since the bite?

It isn't too late. Lyme signs may not start until 2 to 5 months after the bite, and vets treat sick dogs whenever signs appear.19,8,9

Cost of Treatment

One US pet insurer reported average claims of about $600 for Lyme disease and $650 for anaplasmosis in 2017, up from about $350 in 2011.21 Serious cases cost far more. These are older figures from a single insurer, and prices vary by clinic and region.

Preventing Tick-Borne Diseases

  • Use tick prevention all year. US parasite experts recommend year-round tick control, because ticks can be active on any day above about 40°F.1,22,19 A specialist panel agreed unanimously for dogs in Lyme areas, vaccinated or not.8 See flea and tick prevention for dogs.
  • Prefer fast-acting products. Specialists favor products that stop ticks attaching or kill them quickly.8
  • Check for ticks daily after outdoor time, including the ears, eyelids, collar area, under the front legs, between the back legs and toes, and around the tail.5
  • Keep dogs out of tick habitat where you can.20
  • Ask about the Lyme vaccine. Experts disagree on whether every dog in a Lyme area should be vaccinated. Talk to your vet. Either way, use tick prevention year-round.8,14,19

Dogs don't pass these diseases directly to people, but they can bring infected ticks into the home, and dogs can act as early warnings of tick risk for families.7,14,10

Frequently Asked Questions

Can a dog recover from a tick-borne disease?

Most dogs do, especially when treated early. Lyme arthritis, anaplasmosis and acute ehrlichiosis usually respond within days to a few weeks of antibiotics. Kidney-related Lyme disease and chronic infections are harder to treat.

How soon after a tick bite would a dog get sick?

Usually 1 to 3 weeks or longer. Lyme disease can take weeks to a few months to cause signs, and many infected dogs never get sick at all.

What are the stages of Lyme disease in dogs?

Dogs don't follow the stages seen in people. Most infected dogs have no signs, some develop lameness and swollen joints, and a rare few get a serious kidney disease.

What is Lyme nephritis?

It is a rare kidney disease linked to Lyme infection that causes protein loss in the urine. It is serious and can be fatal, so vets check urine protein in dogs that test positive.

What is the life expectancy of a dog with a tick-borne disease?

Most dogs that recover from Lyme arthritis, anaplasmosis or acute ehrlichiosis live normal lives. Lyme kidney disease and chronic ehrlichiosis can shorten life. Your vet can give you an outlook for your dog.

How much does it cost to treat a tick-borne disease?

One insurer reported average claims of about $600 to $650 in 2017 for Lyme disease and anaplasmosis. Severe cases cost much more, and prices vary by clinic and region.

Is 4 months after a tick bite too late to treat?

No. Lyme signs may not appear until 2 to 5 months after a bite, and vets treat sick dogs whenever signs show up.

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Sources and further reading

This article was rewritten and fact-checked on October 30, 2026 against current veterinary references and specialist guidelines:

  1. Companion Animal Parasite Council. Ticks. CAPC Guidelines, updated March 2023.
  2. Palerme JS (reviewed by Carnevale J). Ehrlichiosis in Dogs. Merck Veterinary Manual (professional version), full review September 2025, updated June 2026.
  3. Carter PD, Rolls P. Babesiosis in Animals. Merck Veterinary Manual (professional version), full review March 2022, updated July 2026.
  4. Allen KE. Old World Hepatozoonosis and American Canine Hepatozoonosis. Merck Veterinary Manual (professional version), full review March 2022, updated July 2026.
  5. Centers for Disease Control and Prevention. Preventing Ticks on Pets. CDC, May 15, 2024.
  6. Palerme JS (reviewed by Carnevale J). Anaplasmosis in Dogs. Merck Veterinary Manual (professional version), full review September 2025, updated June 2026.
  7. Roman N. Lyme Disease (Lyme Borreliosis) in Dogs. Merck Veterinary Manual (pet owner version), full review June 2026.
  8. Littman MP, Gerber B, Goldstein RE, Labato MA, Lappin MR, Moore GE. ACVIM consensus update on Lyme borreliosis in dogs and cats. J Vet Intern Med. 2018;32(3):887-903.
  9. Neer TM, Breitschwerdt EB, Greene RT, Lappin MR. Consensus statement on ehrlichial disease of small animals from the Infectious Disease Study Group of the ACVIM. Journal of Veterinary Internal Medicine 16:309-315, 2002 (IVIS ACVIM consensus collection).
  10. Palerme JS (reviewed by Carnevale J). Rocky Mountain Spotted Fever in Dogs. Merck Veterinary Manual (professional version), full review September 2025, updated June 2026.
  11. Morrison BJ. Babesiosis in Dogs: Symptoms and Treatment. PetMD, September 18, 2026.
  12. Little S, Braff J, Place J, Buch J, Dewage BG, Knupp A, Beall M. Canine infection with Dirofilaria immitis, Borrelia burgdorferi, Anaplasma spp., and Ehrlichia spp. in the United States, 2013-2019. Parasites & Vectors, January 2021.
  13. Lappin MR. Update on Select Tick Borne Diseases in Dogs and Cats. Latin American Veterinary Conference, Lima, 2022 (IVIS, March 1, 2023).
  14. Companion Animal Parasite Council. Lyme Disease. CAPC Guidelines, updated May 2019.
  15. Cornell University College of Veterinary Medicine. Anaplasmosis (Riney Canine Health Center). Cornell University, undated.
  16. Barnes C, Williams K, Llera R, Ward E. Ehrlichiosis in Dogs. VCA Animal Hospitals, updated July 30, 2025.
  17. Companion Animal Parasite Council. 2025 Annual Pet Parasite Forecasts. CAPC, 2025.
  18. Labato MA. Lyme Borreliosis in Animals. Merck Veterinary Manual (professional version), reviewed May 2026, updated August 2026.
  19. Cornell Richard P. Riney Canine Health Center. Lyme disease. Cornell University College of Veterinary Medicine.
  20. Moriello KA. Ticks of Dogs. Merck Veterinary Manual (pet owner version), reviewed June 2018, updated September 2024.
  21. Petplan (PRWeb release). On the Uptick: Pet Insurance Company Cites Increase in Lyme Disease Claims, Cost. InsuranceNewsNet, April 2, 2018.
  22. Companion Animal Parasite Council. Ehrlichia spp. and Anaplasma spp. CAPC Guidelines, updated June 2015.

About this article

Last updated : fully rewritten using ACVIM consensus statements on Lyme disease and ehrlichiosis, CAPC guidelines, the Merck Veterinary Manual, Cornell University, the CDC, a 2021 study of more than 144 million US dog test results, IVIS-hosted proceedings, VCA, PetMD and an insurer report; added the research summary, a diseases at a glance table, timing after a bite, testing, treatment, cost, key takeaways and FAQ.

This page is for general information and is not a substitute for an exam by your veterinarian.