Leptospirosis in Dogs

Key takeaways

  • Dogs catch lepto from the urine of infected animals, mostly via water or soil.
  • It occurs in cities and backyards, not just the countryside.
  • Signs: fever, lethargy, vomiting, thirst changes and jaundice.
  • Most dogs survive with early antibiotics and supportive care.
  • A yearly vaccine is recommended for all dogs.

Leptospirosis is a bacterial infection that dogs catch from the urine of infected animals, usually through contaminated water or soil entering the mouth, eyes or broken skin.1,2,3 Rats, raccoons, skunks, other wildlife and livestock carry it, and it occurs in cities, suburbs and backyards as well as the countryside.4,5,6 Signs start about 2 to 14 days after exposure and include fever, lethargy, poor appetite, vomiting, changes in thirst and urination, muscle pain and jaundice.7,8 It most often causes sudden kidney injury and can also damage the liver and, in severe cases, the lungs.9,7 Treatment with antibiotics and supportive care, sometimes dialysis, saves most dogs when started early.4,10 It can spread to people, though spread from dogs is rare. A yearly vaccine is now recommended for all dogs.6,7

See a vet the same day if your dog has:

  • Fever, lethargy, vomiting or refusal to eat, especially after swimming, drinking from puddles or contact with wildlife or rats8,5
  • Drinking or urinating much more or much less than usual8,9
  • Yellow gums or eyes3,4
  • Coughing or trouble breathing, which can mean bleeding in the lungs and is an emergency7,9

Vets often start treatment before test results come back, because kidney damage can become permanent within days.8 Wear gloves when cleaning up urine from a dog that might have lepto.3

What the Research and Guidelines Say

  • All dogs are at risk. The 2023 ACVIM consensus reports cases in puppies as young as 11 weeks, inadequately vaccinated dogs and "small breed dogs from urban areas."7
  • Exposure is common. A 2024 study of 1,345 unvaccinated US dogs in five regions found 11.6% had antibodies to Leptospira, a sign of past exposure, about 10 times the rate for heartworm. The study was funded by an animal-health company.11
  • Unvaccinated dogs get sick. In New York City's 2024 surveillance, none of the 23 dogs with a known vaccine history were up to date on lepto vaccination, and 27% of the 33 cases died or were euthanized.6
  • Dialysis helps. In a 2024 study of 22 dogs with lepto-related kidney failure treated with dialysis, 73% survived to go home.12
  • Daycare outbreaks. A 2021 Los Angeles outbreak sickened more than 200 dogs and was linked to dog daycare, according to a 2026 study.13

How Dogs Get Leptospirosis

  • Contaminated water: puddles, ponds, streams and standing water, the most common source2,1
  • Urine-soaked soil and grass, where the bacteria can survive for weeks to months, including in backyards visited by rodents or wildlife4,14
  • Direct contact with the urine of infected animals, bites or eating infected carcasses3,8
  • Places where dogs gather, such as dog parks, boarding kennels, daycare and training facilities4,13

Rats are the most common source in New York City, and worldwide about 30% of rats carry the bacteria.6,14 Cases often rise after heavy rain and flooding.8,15 In the Northeast, lepto is most common in the fall, while in the South it occurs year-round.14

Symptoms of Leptospirosis in Dogs

Some dogs have no signs, while others become severely ill.3,4 Signs include:

  • Fever, lethargy, poor appetite, vomiting and diarrhea8,1
  • Increased or decreased thirst and urination, from kidney injury, the most common form of lepto in dogs9,8
  • Muscle pain, stiffness, back pain or belly pain5,3
  • Jaundice from liver involvement9,3
  • Coughing or breathing difficulty from bleeding in the lungs9,8
  • Bleeding, and eye inflammation9

Diagnosis

Bloodwork often shows sudden kidney changes, liver changes and low platelets.9 Vets confirm lepto with a combination of tests:7,8

  • PCR on blood and urine, ideally collected before antibiotics are given7
  • Antibody tests (MAT), often repeated 1 to 2 weeks apart, because results can be negative in the first week8,7
  • Rapid in-clinic tests, some of which can be positive in vaccinated dogs8

A single negative test doesn't rule lepto out.7

Treatment

Dogs are treated with antibiotics, usually a tetracycline-class antibiotic for 2 weeks, or a penicillin-class antibiotic given by IV if the dog is vomiting.7,9,2 Most need hospital care with IV fluids, anti-nausea medicine, pain relief and close monitoring of urine output.7,3 Dogs whose kidneys stop producing urine may need dialysis at a specialty center.9,7 Other dogs in the home may be given preventive antibiotics.7

Can a Dog Recover From Leptospirosis?

Yes, and the chances are good when it's treated early.4,2 In a German study of 99 dogs with lepto, about two thirds survived. In small studies of dogs with severe kidney injury treated with dialysis, 73% to over 80% survived.16,12,7 Lung bleeding is the most dangerous form, with death rates of up to 70%.7 Some survivors are left with chronic kidney disease. In one study, half of long-term survivors of dialysis developed it.10,3 See kidney disease in dogs.

Can Humans Get Leptospirosis From Dogs?

It's possible but uncommon. Most US human cases come from water recreation or rodents, and New York City has found no dog-to-human transmission in 19 years of surveillance.4,6 If your dog has lepto:7,3,5

  • Wear gloves to clean up urine, and wash your hands after handling your dog.
  • Clean urine spots with a household disinfectant or a solution of 1 part household bleach to 10 parts water.
  • Use a separate toileting area away from where people and children play or garden.
  • Take extra care until 48 hours of antibiotics are done, and see your doctor if you're ill, pregnant or have a weak immune system.

Dogs can keep shedding bacteria in urine for months after recovery if not fully treated.8,9

Prevention

  • Vaccinate yearly. The vaccine covers the four most common types and is recommended for all dogs from 12 weeks of age. See the lepto vaccine.7,3
  • Keep dogs from drinking standing water, puddles and ponds.2,15
  • Control rodents around your home.6,4
  • Choose boarding and daycare facilities that require the lepto vaccine.17

Frequently Asked Questions

Can my dog get lepto from my backyard?

Yes, if rodents or wildlife urinate there. The bacteria can survive in damp soil for weeks to months.

What are the first signs of leptospirosis in a dog?

Fever, lethargy, poor appetite, vomiting and changes in drinking or urination.

How long does leptospirosis take to show up?

Usually 2 to 14 days after exposure.

Can vaccinated dogs get lepto?

Rarely. The vaccine covers the most common types but not all of them.

What kills leptospirosis?

Common household disinfectants and diluted household bleach kill the bacteria on surfaces. Infected dogs need antibiotics.

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Sources and further reading

This article was rewritten and fact-checked on October 23, 2026 against current veterinary references and specialist guidelines:

  1. Williams K, Weir M, Barnette C, Ward E. Leptospirosis in Dogs. VCA Animal Hospitals, updated November 2024.
  2. Cornell Richard P. Riney Canine Health Center. Canine leptospirosis. Cornell University College of Veterinary Medicine, updated November 2024.
  3. Roman N. Leptospirosis in Dogs. Merck Veterinary Manual (pet owner version), June 2026.
  4. American Veterinary Medical Association. Leptospirosis in Dogs (pet owner brochure). AVMA, 2025.
  5. Washington State Department of Health. Canine leptospirosis. Washington State Department of Health.
  6. New York City Department of Health and Mental Hygiene. 2025 Veterinary Advisory #10: Summary of 2024 Canine Leptospirosis Surveillance in New York City. NYC Health, December 2025.
  7. Sykes JE, Francey T, Schuller S, Stoddard RA, Cowgill LD, Moore GE. Updated ACVIM consensus statement on leptospirosis in dogs. Journal of Veterinary Internal Medicine, 2023.
  8. Sykes JE. An Update on the Diagnosis and Management of Leptospirosis. Today's Veterinary Practice, March/April 2025.
  9. Lunn KF. Leptospirosis in Dogs. MSD Veterinary Manual, updated July 2026.
  10. Ioannou A. Leptospirosis: Current Insights and Practical Approaches for Veterinarians. MSPCA-Angell, 2026.
  11. Carithers D, Loebach E, Williams T, Sponseller J, Schreibman A, Platts D. Field assessment of potential exposure of dogs to leptospirosis by measuring antibody titers in dogs: a multisite study in five geographic regions of the United States. Frontiers in Veterinary Science, 2024.
  12. Ioannou A, et al. Retrospective evaluation of 22 dogs with leptospirosis treated with extracorporeal renal replacement therapies (2018-2021). Journal of Veterinary Internal Medicine, 2024.
  13. Quinton A. Dog Daycare Leptospirosis Outbreak in Los Angeles Reveals Broader Public Health Risks. UC Davis News, May 2026.
  14. American Veterinary Medical Association. Updated guidance on canine leptospirosis reflects better understanding of disease. AVMA News, 2024.
  15. Centers for Disease Control and Prevention. About Leptospirosis. CDC, February 2026.
  16. Knöpfler S, Mayer-Scholl A, Luge E, Klopfleisch R, Gruber AD, Nöckler K, Kohn B. Evaluation of clinical, laboratory, imaging findings and outcome in 99 dogs with leptospirosis. Journal of Small Animal Practice, 2017.
  17. American Animal Hospital Association. Update: AAHA guidelines designate Leptospirosis vaccine as core. AAHA NEWStat, January 2025.

About this article

Last updated : written using the 2023 ACVIM consensus statement on leptospirosis, the Merck Veterinary Manual, the CDC, the AVMA, Cornell, New York City surveillance data and 2022 to 2026 research, plus International Veterinary Information Service (IVIS) proceedings and research published 2022 to 2026.

This page is for general information and is not a substitute for an exam by your veterinarian.