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High Liver Enzyme in a Shih Tzu: Is It Cushing's?

Reader Question
Normal reading in blood test for liver/adrenal gland is 15-150 my 6 yr. old female shihtzu's reading is 431. How do I get samples of her urine? Thank you.


Answer from Our Team

A high liver enzyme (often alkaline phosphatase) is common in dogs with Cushing's, but it can also come from liver disease, some medicines and other illnesses. Specialists recommend testing for Cushing's only if a dog also has signs such as heavy drinking, a big appetite, panting or a pot belly.

For a urine sample, use a clean, shallow container or a ladle held under her while she urinates, ideally first thing in the morning, and take it to the vet within a few hours or refrigerate it.

See Cushing's disease in dogs.

This is general information, not a diagnosis. Please follow your own vet's advice.

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