Can Keflex (Cephalexin) Cause Fecal Incontinence in Dogs?

Soft stool and diarrhea are among the most common side effects of cephalexin (Keflex) and many other antibiotics, because they upset the normal balance of gut bacteria. Softer stool is harder to hold, so some dogs pass it without much warning, even while resting. It often settles once the course is finished, but it’s worth calling your vet now rather than waiting.

Please don’t stop the antibiotic without checking first, as the sore needs treating. Your vet may suggest giving it with food, a probiotic made for dogs, or a different antibiotic. Let them know about the incontinence in case it’s connected to her other treatment.

Meanwhile, take her out more often, use washable bedding, and keep her rear clean. If the accidents continue after the course ends, or if she has diarrhea with blood, vomiting, weakness in her back legs or seems unwell, see your vet promptly. See our guides to dog diarrhea and bowel incontinence in dogs.

This is general information, not a diagnosis. Please follow your own vet's advice.